[an error occurred while processing this directive]

Plant Diversity ›› 2009, Vol. 31 ›› Issue (04): 374-382.DOI: 10.3724 SP.J.1143.2009.09093

• 研究论文 • 上一篇    下一篇


杜良成1, 谭宁华2, 许文彦1 , 2 , 娄丽丽1   

  1. 1 内布拉斯加州立大学林肯分校化学系, 林肯内布拉斯加 68588; 2 中国科学院昆明植物研究所 植物化学与西部植物资源持续利用国家重点实验室, 云南昆明 650204
  • 收稿日期:2009-05-11 出版日期:2009-08-25 发布日期:2009-08-25
  • 通讯作者: 杜良成, 谭宁华

Plant Cyclopeptides and Possible Biosynthetic Mechanisms

DU Liang-Cheng1, TAN Ning-Hua2, XU Wen-Yan1 , 2 , LOU Li-Li1   

  1. 1 Department of Chemistry, University of Nebraska-Lincoln, Lincoln, Nebraska 68588 , USA; 2 State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204 , China
  • Received:2009-05-11 Online:2009-08-25 Published:2009-08-25
  • Contact: DU Liang-Cheng, TAN Ning-Hua

摘要: 植物环肽是一个庞大的小分子天然产物家族, 通常由4~10 个氨基酸残基组合而成。该类化合物广泛存在于全球多种植物的根、茎、枝、叶及种子中, 中草药中也时有发现。由于对其生物合成途径及机理研究较少, 环肽分子的利用价值尚未得到有效的开发。和常见的非环状基因编码的多肽或蛋白质相比, 环肽结构更为复杂。本文将对植物环肽的生物合成途径及其机理做初步探讨。

关键词: 植物环肽, 生物合成, 内生菌, 非核糖体环肽

Abstract: Plant cyclopeptides are a large group of small molecular weight natural products, typically with 4 - 10 amino acids, isolated from the leaves , stem barks , roots, and seeds of a wide variety of plant species throughout the world. The peptides are present in many Chinese medicinal plants, and their potentials have not been well exploited because of the lack of knowledge in their biosynthetic origin and mechanism. The cyclopeptides often have complex chemical structures distinct from common polypeptides ( proteins ) that are non-cyclic and gene-coded. This review discussed the potential origin of the cyclopeptides and their possible biosynthetic mechanisms .

Key words: Plant Cyclopeptide