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Plant Diversity ›› 2009, Vol. 31 ›› Issue (05): 461-468.DOI: 10.3724/SP.J.1143.2009.09108

• 研究论文 • 上一篇    下一篇


李军玲1 , 2 , 罗晓东1 , 赵沛基1 , 曾 英1   

  1. 1 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,
    云南昆明 650204; 2 中国科学院研究生院, 北京 100049
  • 收稿日期:2009-06-01 出版日期:2009-10-25 发布日期:2009-10-25
  • 通讯作者: 曾 英

Post-modification Enzymes Involved in the Biosynthesis of Plant Terpenoids

LI Jun-Ling1 , 2 , LUO Xiao-Dong1 , ZHAO Pei-Ji1 , ZENG Ying1   

  1. 1 State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany , Chinese Academy of Sciences, Kunming 650204 , China ; 2 Graduate University of Chinese Academy of Sciences , Beijing 100049 , China
  • Received:2009-06-01 Online:2009-10-25 Published:2009-10-25
  • Contact: ZENG Ying

摘要: 萜类化合物由于其结构类型丰富多样而被称为“terpenome”。除了参与植物生长发育、环境应答等生理过程, 萜类化合物还应用于医药、有机化工等领域。萜类的生物合成大致可分为前体形成、骨架构建以及后修饰三部分, 基本骨架通常由萜类合酶催化形成, 进一步在后修饰酶的作用下产生数以万计的萜类化合物。结合我们对香茶菜二萜生物合成的初步研究结果, 本文主要针对近年来植物萜类生物合成中的一些有代表性的后修饰酶包括P450 单氧酶、双键还原酶、酰基转移酶和糖基转移酶, 进行研究现状分析与展望。

关键词: 萜类合酶, 后修饰, P450 单氧酶, 双键还原酶, 酰基转移酶, 糖基转移酶

Abstract: Terpenoids are called“terpenome”for their structural diversities . Besides their important roles in plant growth, development and environmental responses, terpenoids have been widely used in medicine and organic chemicals . The biosynthesis of terpenoids in plants can be conceptually divided into three discrete processes: the formation of terpene precursors,
the construction of terpene skeletons, followed by the complex post-modifications . After the skeleton construction by terpene synthases (TPS) , diverse reactions catalyzed by the responsible post-modification enzymes result in tens of thousands of terpenoids . In this paper, with our preliminary studies on the biosynthesis of Isodon diterpenes, a number of representative
post-modification enzymes of plant terpenoids formation reported in recent years are reviewed , which include P450 monooxidases, double-bond reductases, acyltransferases and glycosyltransferases .

Key words: Terpene synthases