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Plant Diversity ›› 2010, Vol. 32 ›› Issue (02): 183-188.DOI: 10.3724/SP.J.1143.2010.09214

• 研究论文 • 上一篇    

广东土牛膝的化学成分

廖彭莹1,2,张颖君1,,王一飞3,王东1,杨崇仁1,4   

  1. 1 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室,云南 昆明650204; 2 广西中医学院,广西 南宁530001; 3 暨南大学,广东 广州510632;
    4 维和生物技术研发中心,云南 玉溪653100
  • 收稿日期:2009-11-02 出版日期:2010-04-25 发布日期:2010-06-29
  • 通讯作者: 张颖君

Chemical Constituents of Guangdong TuNiuXi (Eupatorium chinense, Compositae)

LIAO PengYing1,2, ZHANG YingJun1, WANG YiFei3,
WANG Dong1, YANG ChongRen1,4
  

  1. 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China; 2 Guangxi Traditional Chinese Medical University, Nanning 530001, China; 3 Jinan University, Guangzhou 510632, China; 4 Weihe Biotech Research and Development Center, Yuxi 653100, China
  • Received:2009-11-02 Online:2010-04-25 Published:2010-06-29
  • Contact: ZHANG YingJun

摘要: 广东土牛膝为菊科泽兰属植物华泽兰(Eupatorium chinense)的干燥根。从其甲醇提取物中共分离得到11个化合物,其中eupatorin A (1) 为一新化合物,经波谱学方法鉴定为(threo)3Oacetyl1(4hydroxy3methoxyphenyl)2\[4(3hydroxy1(E)propenyl)2, 6dimethoxyphenoxy\]propylβDglucopyranoside。已知化合物分别鉴定为(threo)3hydroxy1(4hydroxy3methoxyphenyl)2\[4(3hydroxy1(E)propenyl)2,6dimethoxyphenoxy\]propylβDglucopyranoside (2),ardisiacrispin A (3),ardisiacrispin B (4),euparone (5),3(2, 3dihydroxyisopentyl)4hydroxyacetophenone (6),12,13dihydroxyeuparin (7),gymnastone (8),N(2′hydroxytetracosanosyl)2amino1, 3, 4trihydroxyoctadec8(E)ene (9),stigmasterol (10)和stigmasterol3OβDglucopyranoside (11)。化合物2-4为首次从菊科植物,5-8为首次从泽兰属植物中分离得到。

关键词: 广东土牛膝;化学成分;Eupatorin A

Abstract: One new compound, namely eupatorin A (1), was isolated from the methanolic extract of Guangdong TuNiuXi, the dried roots of Eupatorium chinense (Compositae). Its structure was determined to be (threo)3Oacetyl1(4hydroxy3methoxyphenyl)2\[4(3hydroxy1(E)propenyl)2, 6dimethoxyphenoxy\]propylβDglucopyranoside on the basis of detailed spectroscopic analysis. In addition, ten known compounds, including (threo)3hydroxy1(4hydroxy3methoxyphenyl)2\[4(3hydroxy1(E)propenyl)2, 6dimethoxyphenoxy\]propylβDglucopyranoside (2), ardisiacrispin A (3), ardisiacrispin B (4), euparone (5), 3(2, 3dihydroxyisopentyl)4hydroxyacetophenone (6), 12,13dihydroxyeuparin (7), gymnastone (8), N(2′hydroxytetracosanosyl)2amino1, 3, 4trihydroxyoctadec8(E)ene (9), stigmasterol (10) and stigmasterol3OβDglucopyranoside (11) were also obtained. This was the first time that compounds 2-4 were reported from Compositae family, while 5-8 were isolated from the genus Eupatorium.

Key words: Guangdong TuNiuXi (Eupatorium chinense)

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