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Plant Diversity ›› 2010, Vol. 32 ›› Issue (05): 409-.DOI: 10.3724/SP.J.1143.201010076

• 研究论文 • 上一篇    下一篇

重要生化反应“转移磷脂酰反应”的研究进展

 苏一兰1、2、3, 文国松1, 李唯奇3   

  1. 1 云南农业大学农学与生物技术学院,云南 昆明650201; 2 红河学院农学系, 云南 蒙自661100;
     3 中国科学院昆明植物研究所,云南 昆明650204
  • 收稿日期:2010-04-12 出版日期:2010-10-25 发布日期:2010-05-17
  • 基金资助:

    国家自然科学基金NSFC (30670474; 30870571)

The Research Progresses of Phospholipase Dmediated Transphosphatidylation

 SU  Yi-Lan-1、2、3, WEN  Guo-Song-1, LI  Wei-Qi-3   

  1. 1 College of Agronomy and Biotechnology Yunnan Agricultural University, Kunming 650201, China;
    2 Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;
    3 Department of Agronomy, Honghe University, Mengzi 661100, China
  • Received:2010-04-12 Online:2010-10-25 Published:2010-05-17

摘要:

转移磷脂酰反应是在磷脂酶D的催化作用下,甘油磷脂和含羟基化合物发生碱基交换生成新的磷脂的反应。该反应为磷脂酶D所特有,被广泛的应用于动物、植物和微生物的脂类代谢、脂类信号研究以及重要生化制剂磷脂的合成工艺中。本文综述了转移磷脂酰反应的反应机制、影响因素、生物学作用及应用现状,讨论了深入研究这一反应所有待揭示的问题,并展望了今后的发展方向。

关键词: 磷脂酶D, 转移磷脂酰作用, 磷脂酸

Abstract:

Transphosphatidylation denotes the process of the head group exchange in glycerophospholipids which is mediated by Phospholipase D (PLD). This is one of an unique characteristics of PLD and has been well studied in the lipid metabolism, lipid signaling and synthesis of phospholipid of plants, animals and microorganisms. In this paper, the current knowledge on transphosphatidylation, mainly focusing on its catalytic mechanism, substrate specificity, and biological function had been concisely reviewed. Moreover, the future development of this issue had also been discussed.

Key words: Phospholipase D(PLD), Transphosphatidylation, Phosphatidic acid(PA)

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