Abstract: Six compounds: morusin (1), mulberrofuran D (2), kuwanon H (3), mulberrofuran K(4), kuwanon G (5), mulberrofuran G (6) were isolated from root bark of Morus alba and their derivatives were prepared. Anti-HIV activity of these fourteen compounds were tested. Morusin, morusin 4''-glucoside and kuwanon H show positive activity.

Key words: Morus alba