Abstract: A new glycoside, named dregeoside, was isolated from the rhizome of Dregea sinensis var. corrugata (Asclepiadaceae). The structure of dregeoside A was deduced on the basis of chemical and spectral evidence as drevogenin A 3 -0-3-0 -methyl- 6 -deoxy- β-D－allopyranosyl－（1→4）-β-D－oleandropyranosyl-（1→4）- β-D－cymaropyranosyl- （1→4）-β-D－cymaropyranoside）．

Key words: Dregea sinensis var. corrugata