Abstract: As a continution of our chemical studies on chinese species of Panax, the present paper deal with the isolation and structural elucidation of four new dammarane saponins together with five known saponins from tbe leaves of Panax iaponicus C. A. Meyer var. major (Burk.) Wu et Feng, it was collected from Qinling Mountain, Shanxi, China. A crude saponin fraction of the ethanol extract of the leaves of this drug was subjected to repeated column chromatography on silica gel and on reversed phase highly porous polymer and Lichroprep Rp--8 (Lobar) column to affordeing nine saponins. In which five known saponins were proyed to be identical with ginseno- side Rd (5 ) (yield: 0.26%), Re (6 ) (0.10%), Rg, (7 ) (0.032%), Rg, (8 ) (0.032%) and ginsenoside F, (9 ) (0. 16%), respectiyely. Other new four saponins were named majoroside F1 (1 ) (0.21%), F2 (2 ) (0.063%), F3 (3 ) (0.023%)and F4 (4 ) (0 .063% ), respectiYely.

Key words: Panax japonicus var. major