Abstract: From crude glucosides of the root of Cynanchum wallichii Weight (chinese name: Duanjieshan), a folk antirheumarthritic and analgetic drug in Yunnan, by treatment with acid five C21-steroidal compounds have been isolated and identified as deacylmetaplexigenin(Ⅰ), caudatin (Ⅲ), rostratamine(Ⅴ), gagamine(Ⅶ) and qingyanshengenin (Ⅸ) respectively. Ⅸ　was isolated from C. otophyllum Shneid, an another folk medicine in Yunnan, and its structure has been elucidated by Mu Quanzhang.

Key words: chemical, component, wallichii