Abstract: One new compound, namely eupatorin A (1), was isolated from the methanolic extract of Guangdong TuNiuXi, the dried roots of Eupatorium chinense (Compositae). Its structure was determined to be (threo)3Oacetyl1(4hydroxy3methoxyphenyl)2\[4(3hydroxy1(E)propenyl)2, 6dimethoxyphenoxy\]propylβDglucopyranoside on the basis of detailed spectroscopic analysis. In addition, ten known compounds, including (threo)3hydroxy1(4hydroxy3methoxyphenyl)2\[4(3hydroxy1(E)propenyl)2, 6dimethoxyphenoxy\]propylβDglucopyranoside (2), ardisiacrispin A (3), ardisiacrispin B (4), euparone (5), 3(2, 3dihydroxyisopentyl)4hydroxyacetophenone (6), 12,13dihydroxyeuparin (7), gymnastone (8), N(2′hydroxytetracosanosyl)2amino1, 3, 4trihydroxyoctadec8(E)ene (9), stigmasterol (10) and stigmasterol3OβDglucopyranoside (11) were also obtained. This was the first time that compounds 2-4 were reported from Compositae family, while 5-8 were isolated from the genus Eupatorium.

Key words: Guangdong TuNiuXi (Eupatorium chinense)