Plant Diversity ›› 2013, Vol. 35 ›› Issue (1): 81-88.DOI: 10.7677/ynzwyj201312057

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Diterpenoids Chemodiversity of the Genus Isodon Spach from Lamiaceae

 LI  Heng-1、3, PU  Jian-Xin-2, LI  Jie-1   

  1. 1 Laboratory of Plant Phylogenetics and Conservation, Xishuangbanna Tropical Botanical Garden, Chinese Academy of
    Sciences, Kunming 650223, China; 2 State Key Laboratory of Phytochemistry and Plant Resource in West China,
    Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China;
    3 University of Chinese Academy of Sciences, Beijiing 100049, China
  • Received:2012-04-26 Online:2013-01-25 Published:2012-05-21


The species of the genus Isodon from Lamiaceae are often rich in diterpenoids with high medicinal value. According to its frame and oxidation level, the chemodiversity of diterpenoid compounds in genus Isodon was investigated in present study. UPGMA analysis showed that Isodon can be divided into two groups: one is the species producing diterpenoids with two or three ring skeletons, the other is producing diterpenoids with four ring skeleton. When the compounds were mapped on the molecular phylogenetic tree, we found that the species producing three cyclic diterpenoids are much older, such as I.lophanthoides and I.lophanthoides var. micranthus, while those producing four cyclic diterpenoids are younger, such as I.adenanthus and I.xerophilus. These results will contribute to finding and exploiting the active ingredients of dierpenoids from the genus Isodon.

Key words: Isodon, Diterpenoids, Chemodiversity, Phylogeny

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